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November 1946

SYPHILIS: A Review of the Recent Literature

Author Affiliations


From the United States Public Health Service and the Johns Hopkins University Venereal Disease Research and Postgraduate Training Center.

Arch Intern Med (Chic). 1946;78(5):592-625. doi:10.1001/archinte.1946.00220050099006

IN THIS annual review1 of the recent developments in the field of syphilology, emphasis is placed on subjects of greatest current importance. The publications that appeared from July 1945 to June 1946 are concerned for the most part with research carried on during the years of the war. The prodigious cooperative study of penicillin therapy under the supervision of the wartime Committee on Medical Research; the development under war-borne emergency of dimercaprol ("BAL"; 2,3-dimercaptopropanol), efficacious in the treatment of arsenical poisoning; increased understanding of biologic false positive reactions to serologic tests for syphilis, and advancements in civilian and military control of syphilis—all these bear the imprint of the war stimulus to scientific advancement. The number of journals available for review from war-devastated Europe is negligible. Merritt, Adams and Solomon2 are the authors of a recently published monograph on neurosyphilis, based largely on their extensive


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