[Skip to Navigation]
February 1947

EOSINOPHILIC GRANULOMA OF BONE: Report of a Case with Multiple Lesions of Bone and Pulmonary Infiltration

Author Affiliations


From the departments of medicine and radiology, Vanderbilt University School of Medicine.

Arch Intern Med (Chic). 1947;79(2):176-184. doi:10.1001/archinte.1947.00220080064003

DURING the past years, approximately 30 cases of eosinophilic granuloma of bone have been reported in the medical literature. Since it has been noted that this condition is confined to the skeleton, often involving only a single bone, it has also been called "solitary granuloma of bone."1 The case herein reported has been under observation for almost three years since the diagnosis was established and is considered noteworthy because of the presence of multiple skeletal lesions and a coexistent pulmonary infiltration. The latter may well be an instance of visceral involvement.

REPORT OF A CASE  The patient was a 31 year old lawyer who was admitted to the Medical Service of Vanderbilt University Hospital on Jan. 6, 1943, complaining of an intermittent headache in the left occipital region, of about seven months' duration, and backache in the lower region, which he had first noticed three months before his admission.

Add or change institution