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September 1947

SARCOIDOSIS: A Clinical and Roentgenologic Study of Twenty-Eight Proved Cases

Author Affiliations

BOSTON; Dean, Emory University School of Medicine ATLANTA, GA.; Consultant Radiologist, Physicians and Surgeons Hospital GLENDALE, CALIF.; Chief of Radiology, Regional Office, U. S. Veterans Administration BROOKLYN

Arch Intern Med (Chic). 1947;80(3):293-321. doi:10.1001/archinte.1947.00220150003001

WHILE serving in an army general hospital which functioned as a center for radiation therapy, we were afforded an opportunity to study a large number of mediastinal tumors. A clinical and histologic diagnosis of sarcoidosis was established in 28 cases. It was thought worth while to assemble this group of cases and assess the values of the clinical and roentgenologic features of the disease. The most pressing problem in the diagnosis of a mediastinal tumor is the differentiation of benign from malignant lymphogranuloma. The factors bearing on this differential diagnosis are presented.

Since Besnier1 described lupus pernio in 1889 and Boeck2 ten years later studied the histologic structure in his cases of "multiple benign sarcoid of the skin," dermatologists have become increasingly aware of the cutaneous features of the disease. It was not until Schaumann8 in 1914 first realized that the cutaneous lesions described by Besnier and

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