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December 1947

Significance of the Extracellular Fluid in Clinical Medicine.

Arch Intern Med (Chic). 1947;80(6):843-844. doi:10.1001/archinte.1947.00220180148014

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


The author of this monograph is well qualified to write on the significance of extracellular fluids in clinical medicine, as he has spent many years investigating certain phases of the subject. He has accomplished the difficult task of translating information of a highly technical nature into language understood by most clinicians.

The first part of the monograph is taken up with the physiology of extracellular fluids, and the nature of the regulatory mechanisms is outlined in a simple but emphatic manner. The second portion is concerned with the clinical significance of the abnormalities which occur in the extracellular fluid system. The author first familiarizes the reader with the features of the extracellular fluid in its normal state and then discusses the relations between abnormalities of this fluid and a number of diseases.

After the reader understands the nature of the extracellular fluid and its regulation by the kidneys, he is

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