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February 1948


Author Affiliations

Parsons, W. Va.

Arch Intern Med (Chic). 1948;81(2):239. doi:10.1001/archinte.1948.00220200127012

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To the Editor:  —The opening sentence of Dr. Chapman and Dr. Shaffer in their paper on "Mercurial Diuretics" which appeared in the Archives (April 1947) is neither in accordance with the facts nor fair to previous workers. They state: "Acute toxicity of mercurial diuretics has been noted frequently, but no extensive investigation of substances to counteract this toxicity has been reported." This topic sentence, of course, immediately conveys the impression that theirs is the first "extensive investigation" of this nature. To set the record straight, I should like to point out that the work of Pines and his associates (Mercurial Diuretics: The Addition of Magnesium Sulfate to Prevent the Toxic Effects of Their Intravenous Administration, Brit. Heart J. 6:197 [Oct.] 1944), cited by Chapman and Shaffer in another regard and published three years before their work, is in my opinion a good deal more extensive than their own investigation and presents a method

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