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August 1948


Author Affiliations

With the technical assistance of Rudolph Stein STATEN ISLAND, N. Y.

Arch Intern Med (Chic). 1948;82(2):175-183. doi:10.1001/archinte.1948.00220260065005

THE CLINICAL study of tremors has been the subject of a great deal of investigation. Tremors occur in a wide variety of conditions. Most observations, however, have been confined to disease states such as Parkinson's disease and multiple sclerosis. In such conditions as thyrotoxicosis, alcoholism and anxiety states a tremor of the outstretched fingers is considered an important, if not a cardinal, clinical sign. That a tremor can also occur in normal persons has long been known but generally overlooked. "My flesh trembleth for fear of the Lord," a quotation taken from the Bible,1 illustrates the antiquity of this observation.

In the course of a study of palmar sweating among soldiers at an army general hospital, it was found that soldiers with an excessive palmar sweat response frequently exhibited pronounced tremors. A study was therefore undertaken to investigate and correlate these phenomena. To study the sweat response, the technic