A PATIENT with unusual manifestations of systemic lymphogranuloma venereum was recently observed in this clinic. The patient had evidence of pericarditis and had supraclavicular and mediastinal lymphadenopathy. The infection was proved by the isolation of the virus.
Rare instances of systemic infection with lymphogranuloma venereum have been reported, but only a few of them have been proved by recovery of the virus.1 This agent has been isolated from the spinal fluid of 1 patient with meningoencephalitis and from the conjunctival exudate in cases of blennorrhea caused by lymphogranuloma venereum.2 It has also been recovered from the blood and spinal fluid of a patient with genital lesions who had no other manifestations of the disease,3 which indicates that the virus may be widely disseminated in the course of this infection. Cutaneous lesions, arthritis and involvement of cervical, supraclavicular, axillary or retroperitoneal lymph nodes have also been described as
SHELDON WH, WALL MJ, SLADE JD, HEYMAN A. LYMPHOGRANULOMA VENEREUM IN A PATIENT WITH MEDIASTINAL LYMPHADENOPATHY AND PERICARDITIS: Isolation of the Virus from the Supraclavicular Lymph Node. Arch Intern Med (Chic). 1948;82(4):410–416. doi:10.1001/archinte.1948.00020040090006
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