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Article
November 1948

TROPICAL EOSINOPHILIC ASTHMA: Report of Two Cases

Author Affiliations

CHICAGO

From the section on medicine of the Outpatient Treatment Department, Veterans Administration, Regional Office, and the Department of Medicine, Northwestern School of Medicine, and the University of Illinois College of Medicine.

Arch Intern Med (Chic). 1948;82(5):422-430. doi:10.1001/archinte.1948.00220280005002
Abstract

OF THE many diseases contracted by Americans in distant countries, tropical eosinophilic asthma seems to be the least known, as only 3 cases have been reported.1 The subject of this study is a brief description of the disease and a report of 2 additional cases in which the condition had been treated as bronchial asthma for years and in which recovery occurred a few days after specific treatment with neoarsphenamine U. S. P.

DEFINITION  Tropical eosinophilic asthma is a disease of tropical and semitropical regions. It is characterized by chronic bronchitis with nonseasonal nocturnal paroxysmal cough, with dyspnea, leukocytosis and high eosinophilia. This disease has been described under various names.2 We suggest the name tropical eosinophilic asthma because it emphasizes the main morbid manifestations.

HISTORY AND GEOGRAPHIC DISTRIBUTION  Tropical eosinophilic asthma was first described by Weingarten2a in India in 1943. Since then it has been recognized as a

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