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Of the 400 pages in this monograph, only a small share are applicable to the clinical problems of the hemolytic diseases. The balance is a most thorough presentation of the current status of the unique characteristics of the mammalian erythrocyte. The material is presented in a critical and scholarly manner and in great detail. It is fascinating for the reviewer—a clinician—to contemplate the amount of research in general physiology devoted to the red cell. In his introduction, Dr. Ponder says that he has been accused of speaking of the red cell as if it were a microcosm, an understanding of which would include an understanding of nearly everything else in the cellular world. He points out aptly that "lysis is a special, if somewhat extreme case of altered permeability; the actions of lysins on red cells is a special case of the action of drug-like substances, the osmotic properties of
Hemolysis and Related Phenomena. Arch Intern Med (Chic). 1949;84(5):838–839. doi:10.1001/archinte.1949.00230050174011
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