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June 1950


Author Affiliations


From the Department of Metabolic Research, Wenner-Grens Institut, Stockholms Högskola.

Arch Intern Med (Chic). 1950;85(6):966-971. doi:10.1001/archinte.1950.00230120075007

THE HYPERLIPEMIA associated with diabetes mellitus is of particular interest because the level of the blood lipid constituents is, to a certain degree, an index of the fat metabolism and shows a relation to some clinical manifestations. In the present paper the relation between the diabetic neuritis and the blood lipid fractions, total fat, cholesterol and lipid phosphorus will be discussed.

Jordan, Randall and Bloor,1 Jordan and Randall2 and Randall3 made determinations of phospholipids, cholesterol and cerebrosides in the femoral, sciatic and posterior tibial nerves of diabetic patients. They state that the lipid constituents in these nerves were considerably reduced as compared with the normal. The results obtained by the authors mentioned, and also the opinion advanced by one of us in a previous paper,4 viz., that diabetic neuritis occurs especially in young, obese patients with a dysplastic habitus, led us to the investigation the results