DURING the last eight years numerous reports have been published on the intravenous use of procaine (novocain®) hydrochloride. In the United States interest has centered mainly on administration in the slow intravenous drip of 0.1 and 0.2 per cent solutions, taking from twenty minutes to an hour and a half. Results have been excellent in the treatment of many traumatic conditions, inflammatory states and pain syndromes. Unfortunately, however, the giving of an infusion of 500 cc. of solution by slow intravenous drip is not practical in a physician's office. It seemed advisable to search for a more potent solution that could be given quickly in small doses. Workers in Europe have reported on the use of 1 per cent solution of procaine hydrochloride intravenously, with good results. It has been given in treatment of asthma,1 angina pectorislb and numerous other conditions, usually in doses of 3 to
HORAN JS. INTRAVENOUS ADMINISTRATION OF TETRACAINE (PONTOCAINE®) HYDROCHLORIDE: Preliminary Report. Arch Intern Med (Chic). 1950;85(6):972–979. doi:10.1001/archinte.1950.00230120081008
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