THE FOLLOWING case reports deal with 2 patients, independently observed, who showed a combination of intracellular methemoglobinemia, sulfhemoglobinemia and hemolytic anemia. There are a few instances in the literature of the coexistence of these two abnormal pigments in the same patient.1 Although it must occur commonly after treatment with certain drugs,2 no well documented reports were found of the spontaneous occurrence of both hemolytic anemia and abnormal intracellular pigments. The present studies were undertaken to elucidate the mechanism of formation of the abnormal pigments in these patients and the possible relationship to excessive destruction of blood.
REPORT OF CASES
—The patient, a 37 year old housewife, was admitted to the Peter Bent Brigham Hospital March 5, 1946 for the study of cyanosis of twenty-one years' duration.Although a premature baby, the patient was entirely normal in growth and development through puberty. She had had no illnesses
ALFRED S. EVANS, NORBERT ENZER, HOWARD A. EDER, CLEMENT A. FINCH. HEMOLYTIC ANEMIA WITH PAROXYSMAL METHEMOGLOBINEMIA AND SULFHEMOGLOBINEMIAReport of Two Cases. Arch Intern Med (Chic). 1950;86(1):22–34. doi:10.1001/archinte.1950.00230130044003
* * Maintenance Notice * *
Maintenance will be performed from 11:00pm CT December 16, 2017 to 4:00pm CT December 17. Please be advised that your site/services may be periodically unavailable during this maintenance window.