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December 1950

CURRENT CONCEPTS OF MALARIA: With a Review of Five Hundred and Ten Admissions to a Veterans Hospital

Author Affiliations

Chief, Medical Service, Veterans Administration Hospital; Assistant Professor of Medicine, University of Pittsburgh School of Medicine; Chief of Metabolic Section, Veterans Administration Hospital; Resident, Internal Medicine, Veterans Administration Hospital; ASPINWALL, PA.

From the Medical Service, Veterans Administration Hospital, Aspinwall, Pa., and the University of Pittsburgh School of Medicine, Pittsburgh.

AMA Arch Intern Med. 1950;86(6):837-856. doi:10.1001/archinte.1950.00230180042004

INCIDENCE, ECONOMIC SIGNIFICANCE AND MILITARY IMPORTANCE OF MALARIA  MALARIA is an important disease in the United States and the world. It is widely distributed in all tropical and subtropical countries and over many temperate regions. Prevalence of the different etiological agents varies somewhat geographically. Plasmodium vivax (the vector of tertian malaria) has the widest distribution and is the prevailing species in temperate zones. Plasmodium malariae (the cause of quartan malaria) is comparatively rare; it is mainly a parasite of subtropical and temperate areas. Plasmodium falciparum (the agent of malignant tertian malaria) is encountered chiefly in heavily infected districts in the warmer parts of the world, and the disease it causes has been called "tropical malaria." These three are the important malarial parasites for the human race. Plasmodium ovale is a rare species which causes a mild form of tertian malaria. Plasmodium knowlesi is normally a parasite of rhesus monkeys but