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January 1951


Author Affiliations


From the Medical and Pathology Departments, Veterans Administration Hospital, Oakland, Calif.

AMA Arch Intern Med. 1951;87(1):79-96. doi:10.1001/archinte.1951.03810010089007

HYPERLIPEMIA denotes an abnormal increase in the neutral fat of the serum. When of sufficient degree, it can be easily detected on gross inspection of a specimen, the serum losing its usual transparency and becoming milky or creamy in appearance. A distinction must be made between true hyperlipemia and the group of conditions in which other blood lipid fractions are characteristically increased, as, for example, cholesterol and phospholipids; in these circumstances the serum never assumes a milky or creamy appearance. Thannhauser1 points out that the term "hyperlipemia" should be reserved exclusively for an abnormal increase of neutral fat in the serum, while the terms "hyperlecithemia" and "hypercholesteremia" should signify the increase of these respective lipids. Whereas in essential xanthomatosis only cholesterol and lecithin are mainly increased without true hyperlipemia, in the latter condition there are usually present also hypercholesteremia and hyperlecithemia.

Postprandial hyperlipemia is a normal physiological phenomenon following