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Article
August 1952

PRESENT CONCEPTS AND RECENT ADVANCES IN ACUTE POLIOMYELITIS

AMA Arch Intern Med. 1952;90(2):271-279. doi:10.1001/archinte.1952.00240080137014
Abstract

THIS REVIEW is primarily concerned with the present concepts and recent additions to knowledge of the pathogenesis and epidemiology of poliomyelitis. These can be termed the biological aspects of poliomyelitis, and in this field a number of experimental laboratories have been extremely busy during the past few years. Eventually the new facts should find more clinical application than can be assigned to them now, for one must still admit that there are no more immediate measures available for the prevention and cure of the acute disease than existed in the times of Medin and Wickman, 80 and 40 years ago, respectively.

THE POLIOMYELITIS VIRUS  Of primary importance in work on the poliomyelitis virus is the discovery by Enders and his associates, at the Children's Hospital in Boston, that poliomyelitis viruses can be propagated in non-nervous-tissue culture.1 This is a new concept for those who have held that poliomyelitis virus

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