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September 1952

OBSCURE FEVER CAUSED BY CARCINOMA OF THE KIDNEY: A Possible Explanation for the Difficulties in Diagnosis

Author Affiliations


From the Departments of Medicine and Urology, Lebanon Hospital.

AMA Arch Intern Med. 1952;90(3):395-401. doi:10.1001/archinte.1952.00240090116011

IT IS WELL known that malignant tumors of the kidneys are particularly prone to cause fever.1 However, in those cases of fever caused by renal carcinoma, the diagnosis is extremely difficult and often missed. We believe the difficulties arise because in many of these cases the kidney tumors may cause little or no defect in the pelves or calyces. They apparently expand laterally rather than medially, and, therefore, the only change in the pyelogram may be a displacement of the kidney or an increase in its size.

To substantiate this concept, we have analyzed the cases in the literature in which retrograde pyelograms have been done and are reporting one case of our own.

ANALYSIS OF LITERATURE  In analyzing the literature, it is necessary to limit the discussion to those cases completely studied, especially with reference to retrograde pyelograms.Creevy1d presented two cases of fever with hypernephroma. The