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November 1952

ACUTE BLASTOMYCOTIC PNEUMONIA: Report of a Fatal Case of Twenty Days' Duration

Author Affiliations


From the Departments of Pathology, Medicine, and Dermatology and Syphilology of The Medical College of Alabama, and from the St. Vincent's Hospital.

AMA Arch Intern Med. 1952;90(5):718-724. doi:10.1001/archinte.1952.00240110144013

THE SPECIAL features of the case of acute blastomycosis here reported, in contradistinction to the usual cases of fatal blastomycosis, are two, namely, the acuteness and shortness of the clinical course, 20 days, and the complete confinement of the disease to the lungs. In many fatal cases the disease is of months' duration and massive pleural blastomycosis is present about that lobe where the infection is presumed to have begun. Moreover, it is common to encounter blastomycosis of bone and subcutaneous tissues, even brain, indicating hematogenous spread.1

The acuteness of the disease makes necessary the clinical differential consideration of many acute pulmonary infections. Such consideration is unnecessary in most cases of generalized blastomycosis, since the nature of the disease may be suggested by the extrapulmonic lesions.


Clinical History.  —A 41-year-old white seamstress was admitted to the hospital on June 9, 1951, with the chief complaint

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