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September 1953

SHEEHAN'S SYNDROME (POSTPARTUM PANHYPOPITUITARISM): Report of a Case and Comment on Clinical Management

Author Affiliations


AMA Arch Intern Med. 1953;92(3):442-445. doi:10.1001/archinte.1953.00240210146010

A CASE of Sheehan's syndrome (postpartum panhypopituitarism) is presented, with observations on treatment. The patient showed evidence of secondary thyroid, adrenal, and gonadal failure. Combined stimulation and replacement therapy restored the patient to health.

Mrs. E. H., age 44, was admitted to St. Joseph's Hospital, Vancouver, Wash., on Oct. 10, and was discharged on Nov. 8, 1952.

The chief complaints, as given by the patient's mother, were nausea and vomiting, drowsiness, extreme weakness, and mental confusion.

The present illness began about five months before admission, when the patient's mother noted that she was becoming irritable, was easily upset by small troubles, and had a capricious appetite. She had always been good natured before this time. Her dentist had refused to extract her carious teeth unless she would take thyroid and iron; thyroid had been advised a year before but the patient had taken it very haphazardly and finally stopped taking

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