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April 1954

SYPHILIS: Review of the Recent Literature

Author Affiliations

PHILADELPHIA; WILMINGTON, DEL. With the Collaboration of Frank W. Reynolds, M.D., and T. Guthe, M.D., Geneva, Switzerland

From the University of Pennsylvania, Departments of Dermatology, School of Medicine, Donald M. Pillsbury, M.D., Professor; Graduate School of Medicine, Herman Beerman, M.D., Chairman, and the Institute for the Study of Venereal Disease, Norman R. Ingraham, M.D., Director.

AMA Arch Intern Med. 1954;93(4):571-628. doi:10.1001/archinte.1954.00240280091010

THE CONTENT of this, the 18th annual review of syphilis, covering the period July 1, 1952, to July 1, 1953, continues to reflect the chief interest of the previous period.1 There do not appear to be any outstanding discoveries, but the published and unpublished work on the phenomenon of treponemal agglutination in the serodiagnosis of syphilis offers tantalizing conjecture of what the future holds in the field of specific serodiagnosis of syphilis. General problems of serodiagnosis continue to receive adequate attention, but the large number of publications on the treponemal immobilization test (TPI test) indicates how the potentialities of this procedure have captured the imagination of workers from various countries. If this test only helps to clarify the problem of false positive reactions, as Moore and his co-workers maintain, the tremendous effort expended in its evaluation will be fully justified. Penicillin treatment of cardiovascular syphilis is now literally on

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