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August 1954


AMA Arch Intern Med. 1954;94(2):264-271. doi:10.1001/archinte.1954.00250020098007

ABDOMINAL viscera are so frequently involved in periarteritis nodosa that a gastrointestinal type has been considered one of the main clinical forms of this disease.* The symptoms considered 8 to be of gastrointestinal origin include abdominal pain, loss of weight, anorexia, nausea, vomiting, abdominal distention, hemorrhage, jaundice, and diarrhea. In general, these complaints can be ascribed to the vascular lesions, which produce either hemorrhage or infarction, although abdominal pain may occur in periarteritis nodosa without grossly demonstrable lesions in the gastrointestinal tract. Many authors † emphasize the fact that the abdominal symptoms may be sufficiently severe to suggest the need for surgical intervention, with the implication that this need is usually not corroborated by the findings at laparotomy.10 Nevertheless, perforation of the gastrointestinal tract due to ulceration secondary to periarteritis nodosa has been described.4 In a review of the literature, no reference has been found to the occurrence

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