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August 1954


AMA Arch Intern Med. 1954;94(2):314-320. doi:10.1001/archinte.1954.00250020148009

CASES of extrarenal hypernephroma are still rare. Reporting of all such cases seems warranted. Ewing, in the first edition of his book, described a group of kidney tumors in general terms as adrenal rest tumors.1

Clinically, true kidney hypernephroma is notable for its slow growth and insidious evolution; consequently, the surgical specimens are relatively large.

Geshichter and Widenhorn, in 1934, reported a review of 900 cases, in which they stated that 90% of granular cell tumors occur under the age of 60 years, whereas less than 65% of the clear cell type had a similar age distribution. The clear cell types were slower-growing tumors.2

Barney,3 in 1939, described rare extrarenal hypernephromata as tumors arising from epithelium and adrenal rests. He was able to find 14 cases of so-called hypernephromata of extrarenal origin. He describes a case in which the patient had a prolonged convalescence after a suprapubic

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