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November 1954

Treatment of Toxic Goiter with Radioactive Iodine.

AMA Arch Intern Med. 1954;94(5):866. doi:10.1001/archinte.1954.00250050180020

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This book is a careful and thoughtful exposition of the problems inherent in the diagnostic and therapeutic use of radioactive isotopes, particularly I131. The book will have its principal value in acquainting physicians not working actively in the field with both physical and physiological problems inherent in the use of radioactive iodine.

A general exposition of radiation physics and the physical requirements of an isotope laboratory is presented. A further section details the physiological basis of the use of radioiodine in the diagnosis and treatment of thyroid disease. The authors have carefully avoided complicating the text with extensive discussion of esoteric and controversial aspects of thyroid function. The remainder of the book is devoted to the consideration of radioiodine therapy of toxic goiter. A good discussion of proposed methods of calculating therapeutic doses is presented. The authors have evidenced a great deal of profitable scepticism concerning the calculation of

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