THE TERM "hemorrhagic disease" covers a diverse group of disorders in which abnormal bleeding is the only common denominator. A few are inherited, many more are acquired, and bleeding may be the major disturbance or may represent only a minor facet of the total picture in the latter group. Interest in anticoagulant therapy, better understanding of normal hemostasis and recent demonstration of immunopathogenic mechanisms have expanded the list of hemorrhagic diseases to over 20 major categories. Controversies about fundamental physiological and biochemical interpretations have added to the difficulties encountered by the practicing physician who goes to the literature for help in evaluating a given clinical problem. Fortunately, all but the newest information in this field has been well summarized and correlated in several recent monographs * and review articles.† The other references cited are designed to guide the reader to a recent article on each disease and test.
The hemorrhagic diseases
OSGOOD EE, KOLER RD, HUGHES ME. DIFFERENTIAL DIAGNOSIS AND TREATMENT OF HEMORRHAGIC DISEASES. AMA Arch Intern Med. 1954;94(6):956–969. doi:10.1001/archinte.1954.00250060090008
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