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In his preface the author includes among his aims the clear presentation of the biochemical processes of disease from the dynamic point of view and the application of this knowledge in diagnosis, prognosis and treatment. By and large these aims are pretty well fulfilled, but, as might be expected in a volume of this scope, there are a number of defects which future editions will probably correct.
The chapters on the metabolic biochemistry of proteins, carbohydrates, lipids, and electrolytes are excellent, and the correlation with clinical disturbances and their management is well developed. The discussion of diabetes, Bright's disease, cirrhosis of the liver, gout, and uremia, in all of which the author has had wide experience and special interest, is comprehensive and practical. At times the author is somewhat dogmatic, for example, on insisting on the infusion of saline or Ringer's solution as the first fluid regardless of the obvious