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Article
June 1955

PAGET'S DISEASE (OSTEITIS DEFORMANS) FOLLOWED FOR TWENTY-ONE YEARS: Report of a Case

Author Affiliations

New York

From the Arthritis Clinic, University Hospital, and Bellevue Hospital Fourth Division; Associate Professor of Clinical Medicine, New York University Post Graduate Medical School.

AMA Arch Intern Med. 1955;95(6):869-872. doi:10.1001/archinte.1955.00250120105014
Abstract

THE CASE briefly reported here has been under our observation for 21 years, thus offering an opportunity to make longterm observations, especially on the rate of enlargement of the head circumference and on the alkaline phosphatase blood levels. A summary of our present knowledge of osteitis deformans is worth restating, and it is briefly as follows.

REVIEW OF OSTEITIS DEFORMANS  Osteitis deformans * is more important in the differential diagnosis of musculoskeletal disorders than is usually recognized. It commonly causes deformity in one or more of the long bones, and, as a result of the deranged body mechanics, may result in joint pain and disability simulating some forms of arthritis. The pathology may also involve the joint structures themselves. The hip joint, directly or indirectly, is the one most commonly involved. In spite of these clinical manifestations, and probably because the disease starts so insidiously, the diagnosis is often made accidentally, in

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