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This is a report of the fifth and final conference on Renal Function and is devoted to three major topics: the nephrotic syndrome, presented by J. A. Luetscher; human kidney transplantation, by B. F. Miller, and acute renal failure, by G. M. Bull. The discussion covers recent physiological and biochemical studies of adrenal hormone mechanisms in edema formation and diuresis, renal ischemia, antibody response to kidney tissue, and specific tubular functions in tubular nephrosis. There are many interesting clinical details in this volume, which should make it attractive to internists as well as to those working in the fundamental aspects of renal physiology, biochemistry, and pathology.