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December 1955

Tubeless Gastric AnalysisAn Evaluation of Azure A Indicator Compound

AMA Arch Intern Med. 1955;96(6):752-756. doi:10.1001/archinte.1955.00250170058008

Several attempts have been made in the past to develop a simple yet accurate method for the detection of hydrochloric acid in the gastric content without intubation.* A quinine indicator resin proved to be useful for this purpose †; however, certain vitamins, steroids, and quinine-containing drinks or medication, by increasing urinary fluorescence, produced falsely high results; the rather troublesome and time-consuming extraction technique for the detection of quinine in the urine was an additional disadvantage.

The introduction of an azure A ionexchange compound by Segal and coworkers 5 seemed to overcome the principal disadvantage of the quinine resin and to reflect the presence or absence of hydrochloric acid satisfactorily. The present report describes our experience with this compound as an index of the presence or absence of hydrochloric acid in the gastric content of 104 patients.

MATERIAL AND METHODS  The patients swallowed a Levin or Rehfuss tube and underwent the