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March 1956

Surgical Physiology of Adrenal Cortex.

AMA Arch Intern Med. 1956;97(3):388-389. doi:10.1001/archinte.1956.00250210134015

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In this short book the author has summarized much of the present-day knowledge concerning the role of the adrenal cortex in the metabolic response to trauma and surgery. The literature on the subject is briefly reviewed, and many of the significant contributions which Dr. Hardy has made are detailed. The material is presented in easily readable form and is well organized and carefully documented.

From a clinical viewpoint it would appear that preoperative assessment of the adrenal-corticoid response to epinephrine has little practical value, while testing with corticotropin (especially intravenously) is more rewarding in terms of predicting the postoperative course. The author has studied the metabolic response of patients to single operations, to staged operations, and to extensive burns. Patients who were subjected to three-stage thoracoplasty reacted to the second and third operation as vigorously as to the first operation. However, convalescence after the third procedure seemed somewhat more prolonged

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