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September 1956


Author Affiliations


From Tufts University School of Medicine and the Arthritis Clinic of the Boston Dispensary.

AMA Arch Intern Med. 1956;98(3):332-339. doi:10.1001/archinte.1956.00250270076009

MOST CURRENT reports on rheumatic diseases deal with treatment; many compare the effects of particular pharmaceutical agents. Properly regarded as fragments of clinical investigation, such reports do not mean that the successful management of rheumatoid arthritis depends on the administration of one or the other medicine. To be sure, several drugs have definite, more or less circumscribed usefulness. Some rheumatoid patients treated with a new preparation may also have been substantially improved at some time. But if one in practice were to rely foremost on his selection of antirheumatic drugs, he would oftener than not make merely a choice of embarrassments.

Rationale  There is as yet no remedy which can be counted upon to arrest rheumatoid arthritis. None has induced remissions as consistently as have either pregnancy or jaundice. But even though Factor X, credited by Hench with reversibility of rheumatoid arthritis, remains unknown, the disease also commonly abates under

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