In many cases of congestion, and in inflammation of the kidney, a spontaneously coagulable material is effused into the tubes and coagulates there forming a cast or mould of the tube... entangles in its meshes any structures which may be there at the time. The characters of the cast will vary... according to the state of the tubes. By observing... we are often able to form a correct notion concerning the nature of morbid changes going on in tubes at the time the cast was formed. It has been stated that the different morbid states of the kidney are but different stages of one and the same disease... a few months' careful study in the wards of a hospital and in the dead-house, will serve to convince any unprejudiced person that the nature of renal disease may be diagnosed in many cases by the microscopical characters of the urinary deposit,
SCHREINER GE. The Identification and Clinical Significance of Casts. AMA Arch Intern Med. 1957;99(3):356–369. doi:https://doi.org/10.1001/archinte.1957.00260030036004
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