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Article
April 1957

Pathologic Physiology: Mechanisms of Disease.

AMA Arch Intern Med. 1957;99(4):670-671. doi:10.1001/archinte.1957.00260040170019

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Abstract

Some months ago, hard pressed to define the peculiar genus "internist," I described him as a general practitioner of medicine attempting to pursue his art without benefit of instruments beyond those required for physical examination, plus the hypodermic syringe and book of prescription blanks. I might have added that to be a good internist or teacher of medicine he needed more than a passing acquaintance with the kind of knowledge contained in Sodeman's text.

With today's insistence on understanding of the reasons behind abnormal functioning of tissues and organs rather than a chief reliance on the morphologic changes detected grossly or microscopically by the pathologist, physiology takes its place as the primary discipline of the student of medicine. No longer will a thorough knowledge of the history, etiologic factors, pathologic changes, and clinical manifestations of an abnormal physical condition suffice in explaining a disease process to students, patients, or the

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