Esophageal ulcer has a well-deserved reputation for seriousness due to the constant threat of hemorrhage and perforation.1 In fact, because of these dangers a radical surgical approach to therapy may be indicated in a portion of cases and has been urged by some clinicians as proper for most cases.2 One notices, however, that recently reported series3,4 of esophageal ulcer patients show a considerably smaller proportion of serious complications than many of the older series.5,6 It is highly unlikely that there has been any change in the behavior of the lesion; rather, it appears that formerly a good many esophageal ulcers made their presence known only through their complications, while more recently the increasing popularity of medical esophagoscopy has served to bring to light many ulcers which otherwise would have gone unrecognized.
Primary esophageal ulcer usually occurs as a single lesion and almost always involves the distal
PALMER ED. Esophageal Ulcer in the Adult: Clinical Aspects and Experiences with Conservative Treatment. AMA Arch Intern Med. 1957;99(5):695–700. doi:10.1001/archinte.1957.00260050023003
Coronavirus Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.
Create a personal account or sign in to: