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May 1957

Micrococcus Tetragenus Septicemia: Report of a Case Including Subacute Bacterial Endocarditis of the Pulmonic Valve and Mycotic Aneurysm, with Autopsy Findings and Review of the Literature

Author Affiliations

New York

From 1st (Columbia University) Medical Division, Bellevue Hospital.

AMA Arch Intern Med. 1957;99(5):824-832. doi:10.1001/archinte.1957.00260050152017

The organism Micrococcus tetragenus (Gaffkya tetragena)1 is a small encapsulated Gram-positive coccus occurring in clusters of four which was discovered by Koch and Gaffky,2 in 1881. It was first thought to be nonpathogenic, but was described by Jakowsky, in 1886, cited by von Ofenheim,4 to cause septicemia. The first reports in the American literature were by Griewe, in 1899, and by Steele, in 1914, both cited by Reimann.5 The subject was reviewed from a clinical and bacteriological viewpoint by Reimann,5-9 in 1935-1937. At this time he reported only 170 cases of infection due to M. tetragenus in the entire literature, and many of these were incomplete case reports. In another review of the subject by Boynton,10 in 1950, there were only 10 authenticated cases of subacute bacterial endocarditis due to M. tetragenus, and Boynton's case (which included septicemia and meningitis), which was reported in some detail with autopsy findings, was