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July 1957

Dermatomyositis: A Review of Nineteen Cases in Adolescents and Children

Author Affiliations

Oklahoma City; Ann Arbor, Mich.

Department of Dermatology, University of Michigan Hospital and Medical School.

AMA Arch Intern Med. 1957;100(1):70-76. doi:10.1001/archinte.1957.00260070084009

Introduction  The purpose of this paper was to review the course of dermatomyositis in 19 adolescents and children seen at the University of Michigan Hospital between 1935 and 1955. The effects of corticotropin (ACTH) and cortisone therapy were assessed. Several previously unemphasized clinical aspects were noted and the pathological picture assayed.

Review  Dermatomyositis is a disease of infrequent occurrence characterized by insidious onset, nonsuppurative inflammation of striated muscles, and death in about one-half of the cases. Although several hundred case reports of this disease have been published since dermatomyositis was described by Wagner, in 1863, most reports are of only one or a few cases. Reviews of the literature have been accomplished by several authors,* including Karelitz and Welt,1 in 1932; Stuckey,2 in 1935; Keller,3 in 1936, and most completely by Schuermann,4 who in 1939 reviewed 263 case reports among which were 47 children. Selander,5

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