[Skip to Navigation]
August 1957

Infections Due to Bacterium Anitratum

Author Affiliations

New Haven, Conn.

From the Department of Medicine, Yale University. Kellogg Foundation Fellow in Medicine (Dr. Rocha); Research Fellow of the American Heart Association (Dr. Guze).

AMA Arch Intern Med. 1957;100(2):272-275. doi:10.1001/archinte.1957.00260080098019

Introduction  Bacterium anitratum is a Gram-negative bacillus having many characteristics of the Enterobacteriaceae but differing in its inability to reduce nitrate. In many laboratories it is still reported as an unidentified Gram-negative bacillus, and its doubtful position in bacteriologic nomenclature has also received some attention, with varying opinions.1-3 Since the original descriptions by Schaub and Hauber 4 and Stuart et al.,5 several papers have described its isolation, cultural and biochemical characteristics, and sensitivities to antibiotics.6-8 Little information has been provided in connection with its pathogenicity for man. The purpose of this paper is to report three cases in which B. anitratum appeared to play a significant pathogenic role.

Bacteriologic Methods 

A. Identification of Bacterium Anitratum.  —The organism is a nonmotile Gram-negative bacillus, with marked bipolar staining. It grows well on desoxycholate agar, with no, or very slow, lactose fermentation and is inhibited on SS (Difco) agar. In

Add or change institution