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September 1957

Race and the Incidence of Acute Myocardial Infarction: Incidence of Acute Myocardial Infarction Among Autopsies of 9064 White and 8003 Negro Patients, with Special Reference to Age, Sex, and Diabetes Mellitus

Author Affiliations

St. Louis

From the Department of Pathology, Washington University School of Medicine, and the laboratories of Homer G. Phillips Hospital.

AMA Arch Intern Med. 1957;100(3):423-429. doi:10.1001/archinte.1957.00260090079010

In a recent study 1-2 of the incidence of acute myocardial infarction in white patients among the cases which came to autopsy at Washington University for the period 1910-1954, several striking facts were apparent. The incidence of acute myocardial infarction had increased markedly over the years, especially among elderly women. The relative incidence had changed from two males to one female in the period 1910-1939 to one to one in the period 1940-1954. Because of these findings, we believe a review of many of the established concepts regarding the incidence of the disease entity is indicated.

One feature that requires further investigation is the incidence among Negroes. Previous reports 3-8 from the United States (including a study by one of us) 8 and Africa9-10 documented a much lower occurrence of coronary arteriosclerotic disease and its complications among Negroes. However, some recent reports 11-12 have suggested a marked increase of

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