[Skip to Content]
[Skip to Content Landing]
Article
November 1957

Acute Renal Failure Due to Scleroderma Kidney Disease: A Report of One Case with Autopsy Findings

AMA Arch Intern Med. 1957;100(5):813-818. doi:10.1001/archinte.1957.00260110129018
Abstract

The appearance of characteristic renal lesions with marked impairment of renal function is not uncommon in periarteritis nodosa and systemic lupus erythematosus.1-6 However, in another collagen disorder, scleroderma, the occurrence of a characteristic kidney lesion together with fatal renal insufficiency is not generally recognized and has been reported only recently.7 The following case illustrates that renal dysfunction may be the only clinical manifestation of visceral scleroderma and that death may result therefrom.

Report of Case 

First Admission (April 6 to April 28, 1954).  — A 39-year-old white male mechanic supervisor was referred to the hospital for treatment of scleroderma.About two years prior to admission he developed generalized myalgia associated with painful, swollen, and numb joints of the hands and feet. Tightness of the skin over the hands, feet, and face appeared and was accompanied by inability to close the hands completely or to open the mouth normally.

×