In 1891 a young Jewish tailor, Case 4,* emigrated to this country from Russia with his wife and began the prologue to a unique chapter in medical history. This young man settled in Albany, N. Y., established himself as a tailor, fathered a family of five children, and later helped to bring his parents and 10 sisters and brothers from Russia. These few facts about this person seem typical enough of the 19th-century immigrant, but he is of particular importance from the physician's viewpoint because he is the keystone of a continuing 36-year study of a familial tendency toward auricular fibrillation.
A survey of all the medical literature on this subject produced descriptions of occurrences of auricular fibrillation among only two families,1,2 both dealing with males within one generation—the first three brothers and the second two brothers. This study now being reported of 113 males and females
GOULD WL. Auricular Fibrillation: Report on a Study of a Familial Tendency, 1920-1956. AMA Arch Intern Med. 1957;100(6):916–926. doi:10.1001/archinte.1957.00260120060007
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