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December 1957

The Pulmonary Obstruction Syndrome in Schistosoma Mansoni Pulmonary Endarteritis: Report of Five Cases

AMA Arch Intern Med. 1957;100(6):965-980. doi:10.1001/archinte.1957.00260120109013

It has been known for many years that infection caused by Schistosoma affects the lungs, but its frequency and importance have received scanty recognition. Dr. Díaz-Rivera and co-workers 1 reported their observations on 12 patients suffering from acute schistosomiasis during the period of maturation and oviposition. They emphasized the explosive gastrointestinal and pulmonary manifestations, clinically confused with various dysenteric diseases, bronchopneumonia, and pulmonary infiltrative eosinophilia. The latter picture suggests a hypersensitivity state as the chief factor governing the clinical and pathological manifestations.

Belleli, of Alexandria, reported the first case of ova in the lungs in a patient suffering from disease caused by Schistosoma haematobium.2 Azmy Bey in Cairo, reported the first two cases of schistosomal cor pulmonale that at postmortem showed a pulmonary arteriosclerosis.3 The pathogenesis of schistosomal pulmonary obstruction syndrome was discussed by Shaw and Ghareeb, in 1938,4 and Lopes de Faria, in 1952.5 Since