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December 1957

The Pathogenesis of Coronary Occlusion.

AMA Arch Intern Med. 1957;100(6):1015. doi:10.1001/archinte.1957.00260120159020

At a time when the hue and cry of the pack hot on the trail of coronary artery disease drifts and floats about among the fluffy molecules and has its pathway confused, the scent greased by fats and waxed by cholesterol, it is indeed refreshing to have a critical review of a very challenging hypotheses of the pathogenesis of coronary artery disease and infarction of the heart based on morphology. In this book Dr. Morgan gives us a critical survey of Prof. J. B. Duguid's view that coronary artery disease is largely thrombogenic in origin. His document is the more impressive, since at the beginning of the study Morgan was firmly convinced that the hypothesis was wrong. As Morgan says with reference to coronary artery disease, "It should not be forgotten that the preoccupation of the physician is the reestablishment of a circulation that has been arrested by tissue changes,

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