[Skip to Navigation]
January 1958

Ciba Foundation Symposium on the Chemistry and Biology of Purines.

AMA Arch Intern Med. 1958;101(1):168. doi:10.1001/archinte.1958.00260130182039

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This book documents the formal papers and ensuing discussions at the Ciba Foundation Symposium held in London in May, 1956. These deliberations about purine chemistry and metabolism appear to have been an outgrowth of an earlier and successful Ciba Symposium devoted to a related topic, the pteridines. That the study of the chemistry and metabolism of purines is extremely active, even competitive, is seen by the depth and scope of the work, reported from governmental, educational, and industrial laboratories alike. Almost half of the papers are probably outside the interest of all but the organic chemist. Nonetheless they are important for pointing the way toward the synthesis of many other purine analogues of biochemical or therapeutic interest. Certain details presented at this symposium, particularly the contribution by G. R. Greenberg, of Western Reserve, concerning the role of folic acid, are sharpening the picture of purine biosynthesis. The cytotoxic purines were

First Page Preview View Large
First page PDF preview
First page PDF preview
Add or change institution