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The changes in the pulmonary vasculature found in congenital and acquired heart disease have long been known. However, with the advent of cardiac surgery our understanding of the processes involved has become a problem of practical importance. Even though an extensive literature on the subject has accumulated, no general consensus of opinion exists as to the etiology of these pulmonary vascular changes, the underlying pathophysiologic mechanisms involved, and the interpretation of the anatomical substrate. This very timely publication is based on the examination of the lungs of forty-one patients with congenital heart disease by the pathologist. A short review of the embryology, anatomy, and physiology of the pulmonary vasculature precedes the description of the microscopic findings of the heart and lungs for each patient.
The histological findings in the lungs are reported in detail and illustrated with blackand-white photomicrographs of good quality and a few schematic drawings. The clinical histories
Wessel HU. Die Lungenarterienbahn bei angeborenen Herzfehlern. AMA Arch Intern Med. 1958;102(2):340–341. doi:10.1001/archinte.1958.00260200168030
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