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October 1958

The Medical Management of Peptic Ulcer

Author Affiliations

Rochester, Minn.

Section of Medicine, Mayo Clinic and Mayo Foundation. The Mayo Foundation, Rochester, Minn., is a part of the Graduate School of the University of Minnesota.

AMA Arch Intern Med. 1958;102(4):594-606. doi:10.1001/archinte.1958.00260210080013

The problem of peptic ulcer is important in the general economy if only by virtue of the fact that 5% to 10% of the population of this country at some time during their lives will have such a lesion. Fortunately, most of these persons do not experience any serious consequence of the disease, and many have little difficulty in controlling its symptoms. However, the morbidity produced by a disease of this magnitude of occurrence makes its recognition vital and calls for intelligent appreciation of the essentials of treatment that render control of the lesion a reasonable possibility.

Were the cause of peptic ulcer more accurately understood, it is likely that its treatment would be more efficacious and less diverse. In a broad sense, two major schools of thought exist with respect to the treatment of ulcer; the first emphasizes a strict ritual of diet, antacid medicines, sedatives, and anticholinergic drugs,

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