Unfortunately, the long life span of man makes it impossible for an investigator to study him throughout his average lifetime. Only segments of man's life are available for study by any one man, and unless succeeding teams of investigators with adequate interest can be gathered to trace the longevity of a group of people, the study will be incomplete. Nevertheless, there are many interesting and important problems available for study in other living models, and so those who desire to study fundamental aspects of the aging process need not fret or be concerned with high costs of experiments. For example, various aspects of aging can be studied in lower forms of living things with short life spans. Once the living experimental model with a relatively short life has been selected, a reliable manifestation of aging offers in next difficulty. A phenomenon which definitely reflects the aging process is not easy
Burch G. Interesting Observations of the Aging Process. AMA Arch Intern Med. 1959;103(1):1–3. doi:10.1001/archinte.1959.00270010007001
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