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March 1959

The Liver and Its Reactions in Africa.

AMA Arch Intern Med. 1959;103(3):513. doi:10.1001/archinte.1959.00270030169033

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This monograph contains the papers presented at the Fourteenth Annual Conference on African Medicine, held in Johannesburg in May, 1958. It is particularly concerned with the special aspects of liver disease seen in the native populations.

Various authors discuss the influence of malnutrition in early life on the metabolism of the liver and its role in increasing the incidence and severity of later hepatic disease. Several authors deal with primary tumors of the liver, pointing out their frequency of occurrence and fulminating course in Africans as compared to Americans and Europeans. The problem of parasitic infections, especially schistosomiasis and amebiasis as they affect the liver is also considered.

Unfortunately, there is some repetition and only a few of the papers present new approaches or are concerned with clinical or laboratory investigations. Particularly interesting are papers dealing with "Steroid Hormone Metabolism in Liver Disease," and "Alterations in Carbohydrate Metabolism Associated with

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