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September 1959

Evaluation of the Adequacy of Needle-Biopsy Specimens of the Kidney: An Autopsy Study

Author Affiliations


From the Departments of Medicine, University of Illinois College of Medicine, the Chicago Medical School, and the West Side Veterans Administration Hospital, and the Departments of Pathology, West Side Veterans Administration Hospital and the Chicago Medical School.

AMA Arch Intern Med. 1959;104(3):353-359. doi:10.1001/archinte.1959.00270090007002

Percutaneous needle biopsy of various organs and tissues has become a useful and important diagnostic procedure. Since the report by Iversen and Roholm,1 in 1939, needle biopsy of the liver has been accepted as a reliable technique for demonstrating structural changes which occur in diseases of this organ.

In 1951, Iversen and Brun described a procedure for needle biopsy of the kidney.2 This was the first of many reports 3 which have contributed valuable information about diseases of this organ. There are, however, only a few studies which deal with the representative nature of the kidney-biopsy specimen.4-6 The study being reported was done to explore the correlations which exist between diagnoses from needle biopsies of the kidney and those from routine autopsy specimens. Similar investigations were done when the value of needle biopsy of the liver was being established.7-10

Material and Methods  This study was begun in June, 1954. At

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