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November 1959

Industrial ToxicologyI. General Principles and New Developments

AMA Arch Intern Med. 1959;104(5):816-826. doi:10.1001/archinte.1959.00270110136018

Because of the increasing complexity of modern industrial technology, the internist is faced with an increasing number of problems in environmental medicine and toxicology. The purpose of this paper is to present both basic principles and new developments in industrial toxicology for the particular benefit of those who have had little previous experience with occupational diseases. No attempt will be made to review all the toxic agents which may be encountered in industry.

The incidence of industrial intoxication is not great and, in the United States, amounts to only about 3% of all industrial accidents and diseases. One gains the impression from foreign publications that it probably occurs more frequently in Italy and Germany. That such intoxications occur at all is owing to several factors: ignorance of the toxic potentialities of the chemicals, disregard for personal safety, and inability to prevent several types of accident.

We will first consider two

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