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January 1960

Transactions of the Third Conference on the Physiology of Prematurity.

AMA Arch Intern Med. 1960;105(1):175. doi:10.1001/archinte.1960.00270130191030

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The high caliber of the two previous Macy Foundation publications presenting the transactions of the first and second conferences on the physiology of prematurity is maintained in this presentation. The general topic of the conference is enzyme biochemistry, with principal attention devoted to the enzyme deficiencies of the premature and newborn infant. In the first section, the enzymatic control of phenylalanine and tyrosine metabolism in the premature, term infant and in the adult is covered in detail. The remaining portion of the volume deals with mechanisms of glucuronide formation in the same subjects. Major attention is focused on bile pigment metabolism and bilirubin glucuronide formation. In this area, the benefits of this type of conference are seen most clearly. As an example, the inability to explain satisfactorily the relative inability of the premature or term infant to conjugate bilirubin entirely on the basis of glucuronosyl transferase deficiency or on the

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