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April 1960

The Use of Peritoneal Dialysis in Acute Methyl Alcohol Poisoning

Author Affiliations

Balboa Heights, Canal Zone

From the Medical Service, Gorgas Hospital, Ancon, Canal Zone. Resident in Internal Medicine, Gorgas Hospital.

AMA Arch Intern Med. 1960;105(4):613-617. doi:10.1001/archinte.1960.00270160111014

It is the purpose of this paper to describe our experience with peritoneal dialysis in the treatment of methyl alcohol poisoning and to review the basis for alkalinization and ethyl alcohol therapy. The clinical picture, pharmacology, and mechanism of toxicity have been adequately discussed previously4; therefore, no attempt will be made to review these aspects of the problem.

Alkalinization was first suggested1 as therapy in 1920, but the general importance of this type of treatment was not recognized until the reports of Chew2 and Røe,3 in 1946. They noted that with this type of therapy the symptoms were often promptly alleviated and the survival rate was increased. Since that time, numerous investigators have confirmed the value of alkalinization clinically and experimentally. Bennett,4 in 1951, treated a series of 323 cases and left no doubt as to the efficacy of this method of treatment. He pointed out that large amounts of

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