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November 1960

Useful Drugs in the Treatment of Cancer

Author Affiliations

Bethesda, Md.

Arch Intern Med. 1960;106(5):663-678. doi:10.1001/archinte.1960.03820050075014

Introduction  In this review I propose to comment on those anticancer drugs which may now be considered a part of the practice of medicine and attempt to summarize what they may be expected to achieve. This resumé will be preceded by some general remarks on the management of cancer patients and followed by a consideration of some of the current research problems in cancer chemotherapy.

General Remarks  The internist is beginning to assume a major role in the study and management of the patient with cancer. The internist has always been keenly alert to the problem of early diagnosis of cancer, but in earlier years there was a considerable tendency to transfer the responsibility for management to the surgeon and radiologist. Hematologists, of course, maintained a considerable interest in the leukemias and lymphomas, but the patient with known disseminated cancer of nonhematopoietic origin was rarely admitted to the wards of

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